Hi,
I do a similar thing, however in my case I have 2 HDDs in most of my machines. My second drive (data) is Waaaay bigger, so what I do is create a folder on it named "Sync" which is what I synchronize. I then go to my profile and move the various folders locations (Pictures, Documents etc) to Sub-Folders of my Sync folder.
This way, not only is all of my data stored on the second (larger) drive, but I get an easy way to control what is synced.
HTH